It’s true that acne is most common in teenagers and young adults, but you can experience breakouts even in your 50s.

And here’s the kicker: the acne you experience as an adult may not be the same as the acne you experienced as a teenager.

There are many reasons for adult acne breakouts, including

The balance of estrogens and testosterone plays a big role in your acne

Estrogens help lower testosterone levels. Too much testosterone can increase sebum (oil) production in your skin. And too much sebum can mean clogged pores and acne breakouts, including blackheads, whiteheads, and blemishes.

The levels of your estrogens are lowest right before your period and later during menopause.


ALTRENO lotion is the first and only tretinoin available in a lotion formulation. The lotion helps hydrate your skin. But what does
tretinoin do?

Tretinoin, the acne-fighting ingredient in ALTRENO lotion, is
a retinoid.

Retinols, retinoids, what’s the difference?

Both are derived from Vitamin A, however:

  • Retinols are found in some cosmetics and beauty products and are not FDA approved to fight acne
  • Retinoids are clinically proven and FDA approved to treat acne

The lotion formulation of ALTRENO contains

  • Soluble collagen
  • Glycerin
  • Sodium hyaluronate

Before you use ALTRENO, tell
your healthcare provider if you
are allergic to fish or if you get hives or itching during treatment with ALTRENO.

Sodium hyaluronate is a form of hyaluronic acid. Hyaluronic acid is known to hydrate the skin as well as reduce water loss.


ALTRENO lotion stimulates renewal of skin cells to treat your acne.

ALTRENO lotion improves acne and reduces breakouts. It is believed to do this in 2 ways.

  • It unclogs pores by increasing the rate at which new skin cells are produced and shed.
  • It prevents dead skin cells from clumping together and clogging pores in the first place.

ALTRENO lotion has been proven in clinical studies

  • Significant reductions in both blackheads and whiteheads
  • The number of blemishes was reduced by more than half
  • The most common side effect was dry skin (4% of patients)


First, gently wash your skin with a cleanser and pat dry.

Next, apply a small amount (about the size of a pea) and spread it in a thin layer over the affected area.

Use ALTRENO lotion once daily, any time that’s convenient for you. Because it disappears so quickly into your skin, you can even use it under makeup.


With your ALTRENO lotion prescription there is no private or government insurance coverage, meaning you face fewer hassles. There are no copays, coupon cards, or need for reimbursement. You simply pay around $115 for your prescription, which lasts about 3 months.

You live a busy life. So it’s important that getting your prescription is as easy as possible. Maybe you prefer the convenience of home delivery. Or you like dropping by your neighborhood pharmacy while running errands. However you choose, whatever way fits your schedule best, it’s possible with ALTRENO lotion.


ALTRENO (tretinoin) lotion, 0.05% is a prescription medicine used on the skin (topical) to treat people with acne (blackheads, whiteheads, and other pimples).


It is not known if ALTRENO is safe and effective in children under 9 years of age.

ALTRENO is for use on the skin only. Do not use it in your eyes, mouth, or vagina.

What should I tell my healthcare provider before using ALTRENO?

Before you use ALTRENO, tell your healthcare provider about all of your medical conditions, including if you:

  • are allergic to fish. ALTRENO contains fish proteins. Tell your healthcare provider if you get hives or itching during treatment with ALTRENO.
  • have eczema or any other skin problems.
  • have a sunburn.
  • are pregnant or plan to become pregnant. It is not known if ALTRENO will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known if ALTRENO passes into your breast milk.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Certain medicines, vitamins, or supplements may make your skin more sensitive to sunlight. Tell your healthcare provider about any cosmetics you use, including moisturizers, creams, lotions, or products that can dry out your skin.

What should I avoid while using ALTRENO?

  • You should avoid sunlamps, tanning beds, and ultraviolet light during treatment with ALTRENO.
  • Minimize exposure to sunlight. If you have to be in the sunlight or are sensitive to sunlight, use a sunscreen with an SPF of 15 or more and wear protective clothing and a wide-brimmed hat to cover the treated areas.

What are the possible side effects of ALTRENO?

ALTRENO may cause serious side effects, including:

Skin Irritation: ALTRENO may cause irritation, including skin dryness, pain, redness, excessive flaking or peeling. If you develop these symptoms, your healthcare provider may tell you to stop using ALTRENO for a while, decrease how often you use it, or stop it altogether. Avoid applying ALTRENO to skin that is affected by eczema or sunburned.

  • These are not all the possible side effects of ALTRENO.
  • Call your healthcare provider for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs. Visit or call 1-800-FDA-1088.

Please click here for full Prescribing Information, including Patient Information.